Assay Detail
Binding
CHEMBL5372173
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of XOD (unknown origin) using xanthine as substrate preincubated for 30 mins followed by xanthine addition measured after 30 mins by microplate reader
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery and Characterization of Moracin C as an Anti-Gouty Arthritis/Hyperuricemia Candidate by Docking-Based Virtual Screening and Pharmacological Evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.90 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1164729 | FEBUXOSTAT | 4.0 | 1 | 6.80 |
| CHEMBL2018876 | MORACIN C | — | 1 | 6.60 |
| CHEMBL463241 | MORACIN D | — | 1 | 5.29 |
| CHEMBL453280 | ISOFORMONENTIN | — | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1164729 | FEBUXOSTAT | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL2018876 | MORACIN C | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL463241 | MORACIN D | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL453280 | ISOFORMONENTIN | IC50 | = | 13000.0 | nM | 4.89 |