Assay Detail
Functional
CHEMBL5372210
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human OVCAR-5 cells assessed as inhibition of cell growth for 72 hrs by CellTiter-Blue cell viability assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OVCAR-5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.20 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.44 |
| CHEMBL3758224 | — | — | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 3.6 | nM | 8.44 |
| CHEMBL3758224 | — | IC50 | = | 11.0 | nM | 7.96 |