Assay Detail
Binding
CHEMBL5372452
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Inhibition of PDK (unknown origin) incubated for 10 mins in presence of ATP
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Reprogramming Energy Metabolism with Synthesized PDK Inhibitors Based on Dichloroacetate Derivatives and Targeted Delivery Systems for Enhanced Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.58 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231132 | — | — | 1 | 7.06 |
| CHEMBL4082531 | — | — | 1 | 6.10 |
| CHEMBL414883 | RADICICOL | — | 1 | - |
| CHEMBL192894 | — | — | 1 | - |
| CHEMBL306823 | SODIUM DICHLOROACETATE | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231132 | — | EC50 | = | 87.0 | nM | 7.06 |
| CHEMBL4082531 | — | EC50 | = | 800.0 | nM | 6.10 |
| CHEMBL414883 | RADICICOL | EC50 | = | 1097000.0 | nM | - |
| CHEMBL192894 | — | EC50 | = | 648000.0 | nM | - |
| CHEMBL306823 | SODIUM DICHLOROACETATE | EC50 | = | 180000.0 | nM | - |