Assay Detail
Binding
CHEMBL5372453
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Inhibition of PDK (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Reprogramming Energy Metabolism with Synthesized PDK Inhibitors Based on Dichloroacetate Derivatives and Targeted Delivery Systems for Enhanced Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.99 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL316388 | — | — | 1 | 7.80 |
| CHEMBL3727577 | — | — | 1 | 7.46 |
| CHEMBL1236255 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL316388 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL3727577 | — | EC50 | = | 35.0 | nM | 7.46 |
| CHEMBL1236255 | — | EC50 | = | 2000.0 | nM | 5.70 |