Assay Detail
Functional
CHEMBL5372613
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Phototoxicity against human AGS cells assessed as reduction in cell growth preincubated with compound for 24 hrs followed by blue light irradiation at 468 nm for 7 mins 30 sec and measured after 48 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | AGS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Fungal Anthraquinone Photoantimicrobials Challenge the Dogma of Cationic Photosensitizers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.82 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289277 | EMODIN | — | 1 | 5.82 |
| CHEMBL5407758 | — | — | 1 | - |
| CHEMBL457945 | — | — | 1 | - |
| CHEMBL5434610 | — | — | 1 | - |
| CHEMBL1973073 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289277 | EMODIN | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5407758 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL457945 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL5434610 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL1973073 | — | EC50 | > | 25000.0 | nM | - |