Assay Detail
Binding
CHEMBL5373566
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EE-tagged PI3KC2alpha (unknown origin) transfected in HEK293 cells incubated for 20 mins in the presence of ATP by TLC analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (CHEMBL1075102) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.11 | 7.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241857 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241857 | — | IC50 | = | 78.0 | nM | 7.11 |