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Assay Detail

CHEMBL5374066

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Newcastle disease virus Hemagglutinin-Neuraminidase assessed as reduction in hemagglutination activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Avian orthoavulavirus 1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Interplay of Modified Sialic Acid Inhibitors and the Human Parainfluenza Virus 1 Hemagglutinin-Neuraminidase Active Site.
Rota P, La Rocca P, Bonfante F, Pagliari M, Cirillo F, Piccoli M, Ghiroldi A, Franco V, Pappone C, Allevi P, Anastasia L.
ACS Med Chem Lett (2023) 14 : 1383 -1388
PubMed 37849540 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.29 6.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL514002 1 6.91
CHEMBL5429016 1 5.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL514002 IC50 = 124.0 nM 6.91
CHEMBL5429016 IC50 = 2140.0 nM 5.67