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Assay Detail

CHEMBL5374069

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human parainfluenza virus type 3 Hemagglutinin-Neuraminidase using MUN as substrate assessed as reduction in neuraminidase activity incubated for 30 mins by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human respirovirus 3
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Interplay of Modified Sialic Acid Inhibitors and the Human Parainfluenza Virus 1 Hemagglutinin-Neuraminidase Active Site.
Rota P, La Rocca P, Bonfante F, Pagliari M, Cirillo F, Piccoli M, Ghiroldi A, Franco V, Pappone C, Allevi P, Anastasia L.
ACS Med Chem Lett (2023) 14 : 1383 -1388
PubMed 37849540 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4745230 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4745230 IC50 = 570.0 nM 6.24