Assay Detail
Binding
CHEMBL5376040
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of aromatase in human placental using [1beta-3H] as substarte incubated for 1 hrs by scintillation counting analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Placenta |
| Subcellular | Microsome |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Combating breast cancer with non-steroidal aromatase inhibitors (NSAIs): Understanding the chemico-biological interactions through comparative SAR/QSAR study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.74 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL317221 | — | — | 1 | 4.74 |
| CHEMBL491692 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL317221 | — | IC50 | = | 18323.14 | nM | 4.74 |
| CHEMBL491692 | — | IC50 | = | 946237161.37 | nM | - |