Assay Detail
Binding
CHEMBL5376053
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant aromatase in JEG-3 cells using [1beta-3H]androstenedione as substarte incubated for 3 hr by scintillation counting analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | JEG-3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Combating breast cancer with non-steroidal aromatase inhibitors (NSAIs): Understanding the chemico-biological interactions through comparative SAR/QSAR study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.20 | 4.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3622062 | — | — | 1 | 4.20 |
| CHEMBL3622063 | — | — | 1 | - |
| CHEMBL5397563 | — | — | 1 | - |
| CHEMBL5398997 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3622062 | — | IC50 | = | 62517.27 | nM | 4.20 |
| CHEMBL3622063 | — | IC50 | = | 99083194.49 | nM | - |
| CHEMBL5397563 | — | IC50 | = | 156675107.01 | nM | - |
| CHEMBL5398997 | — | IC50 | = | 749894209.33 | nM | - |