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Assay Detail

CHEMBL5376451

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 24 hrs by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

The evolution of small molecule enzyme activators.
Dow LF, Case AM, Paustian MP, Pinkerton BR, Simeon P, Trippier PC.
RSC Med Chem (2023) 14 : 2206 -2230
PubMed 37974956 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.54 5.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL314854 FINGOLIMOD 4.0 1 5.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL314854 FINGOLIMOD IC50 = 2900.0 nM 5.54