Assay Detail
Binding
CHEMBL5376486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Positive allosteric modulation of recombinant mouse IDOL transfected in mouse P1.HTR cells assessed as increase in Kyn production incubated for 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | P1.HTR |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The evolution of small molecule enzyme activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.68 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL33103 | ACETYLSEROTONIN | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL33103 | ACETYLSEROTONIN | EC50 | = | 20950.0 | nM | 4.68 |