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Assay Detail

CHEMBL5378841

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Upregulation of GDE1 mRNA expression in human HT-29 cells measured after 16 hrs by qPCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HT-29
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.
Adouvi G, Nawa F, Ballarotto M, Rüger LA, Knümann L, Kasch T, Arifi S, Schubert-Zsilavecz M, Willems S, Marschner JA, Pabel J, Merk D.
J Med Chem (2023) 66 : 16762 -16771
PubMed 38064686 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5404648 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5404648 EC50 = 10.0 nM 8.00