Assay Detail
Binding
CHEMBL5379142
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to ILF3 (unknown origin) assessed as dissociation constant at upto 1 uM by SPR method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Interleukin enhancer-binding factor 3 (CHEMBL5465305) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pioneering 4,11-Dioxo-4,11-dihydro-1<i>H</i>-anthra[2,3-<i>d</i>]imidazol-3-ium Compounds as Promising Survivin Inhibitors by Targeting ILF3/NF110 for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.52 | 6.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5411686 | — | — | 1 | 6.79 |
| CHEMBL2105734 | SEPANTRONIUM BROMIDE | 2.0 | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5411686 | — | Kd | = | 163.0 | nM | 6.79 |
| CHEMBL2105734 | SEPANTRONIUM BROMIDE | Kd | = | 571.0 | nM | 6.24 |