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Assay Detail

CHEMBL5379266

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NCI-H1048 cells incubated for 5 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H1048
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H1048 (CHEMBL1075512)
Type CELL-LINE
Organism Homo sapiens

Publication

Design and Development of IKZF2 and CK1α Dual Degraders.
Miyamoto DK, Curnutt NM, Park SM, Stavropoulos A, Kharas MG, Woo CM.
J Med Chem (2023) 66 : 16953 -16979
PubMed 38085607 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.31 7.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5401432 1 7.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5401432 EC50 = 49.0 nM 7.31