Assay Detail
Binding
CHEMBL5379294
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Inhibition of PARP-2 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Advances in Development of Selective Antitumor Inhibitors That Target PARP-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.47 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5398361 | — | — | 1 | 7.06 |
| CHEMBL5401937 | — | — | 1 | 6.78 |
| CHEMBL5432033 | — | — | 1 | 6.52 |
| CHEMBL250490 | — | — | 1 | 6.30 |
| CHEMBL249813 | — | — | 1 | 6.22 |
| CHEMBL250489 | — | — | 1 | 6.21 |
| CHEMBL5427976 | — | — | 1 | 6.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5398361 | — | IC50 | = | 87.0 | nM | 7.06 |
| CHEMBL5401937 | — | IC50 | = | 167.0 | nM | 6.78 |
| CHEMBL5432033 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL250490 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL249813 | — | IC50 | = | 608.0 | nM | 6.22 |
| CHEMBL250489 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL5427976 | — | IC50 | = | 630.0 | nM | 6.20 |