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Assay Detail

CHEMBL5379428

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Functional
Antiproliferative activity against human EKVX cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type EKVX
Confidence 1 — Organism
Curated By Autocuration

Target

EKVX (CHEMBL614487)
Type CELL-LINE
Organism Homo sapiens

Publication

Small Molecule Inhibitors Targeting the "Undruggable" Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective.
Cui Q, Huang C, Liu JY, Zhang JT.
J Med Chem (2023) 66 : 16515 -16545
PubMed 38092421 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL307794 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL307794 IC50 = 6.0 nM 8.22