Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5379470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type EL4
Confidence 1 — Organism
Curated By Autocuration

Target

EL4 (CHEMBL614293)
Type CELL-LINE
Organism Mus musculus

Publication

Small Molecule Inhibitors Targeting the "Undruggable" Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective.
Cui Q, Huang C, Liu JY, Zhang JT.
J Med Chem (2023) 66 : 16515 -16545
PubMed 38092421 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.95 6.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5411841 1 6.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5411841 IC50 = 112.0 nM 6.95