Assay Detail
Functional
CHEMBL5379473
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Cytotoxicity against human SW620 cells assessed as inhibition of cell growth incubated for 48 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW-620 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small Molecule Inhibitors Targeting the "Undruggable" Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.87 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5202359 | — | — | 1 | 9.96 |
| CHEMBL5171746 | — | — | 1 | 9.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5202359 | — | IC50 | = | 0.11 | nM | 9.96 |
| CHEMBL5171746 | — | IC50 | = | 0.17 | nM | 9.77 |