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Assay Detail

CHEMBL5380116

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against influenza A virus A/duck/Hokkaido/Vac-3/2007 (H5N1) infected in MDCK cells assessed as reduction in cytopathic effect incubated for 48 hrs by crystal violet staining based plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

Recent advances of phenotypic screening strategies in the application of anti-influenza virus drug discovery.
Jia H, Hu L, Zhang J, Huang X, Jiang Y, Dong G, Liu C, Liu X, Kim M, Zhan P.
RSC Med Chem (2024) 15 : 70 -80
PubMed 38283223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 4.40 4.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1911316 1 4.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1911316 EC50 = 39800.0 nM 4.40