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Assay Detail

CHEMBL5380136

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Functional
Antiviral activity against recombinant influenza virus WSN harboring PB1 456H codon infected in MDCK cells assessed as reduction in cytopathic effect by fluorescence based analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism unidentified influenza virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

unidentified influenza virus (CHEMBL613128)
Type ORGANISM
Organism unidentified influenza virus

Publication

Recent advances of phenotypic screening strategies in the application of anti-influenza virus drug discovery.
Jia H, Hu L, Zhang J, Huang X, Jiang Y, Dong G, Liu C, Liu X, Kim M, Zhan P.
RSC Med Chem (2024) 15 : 70 -80
PubMed 38283223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5407952 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5407952 IC50 = 300.0 nM 6.52