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Assay Detail

CHEMBL5380468

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human coxsackievirus B4 infected in human H1-HeLa cells incubated for 3 days measured by crystal violet staining based plaque counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Coxsackievirus B4
Cell Type H1-HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

Coxsackievirus B4 (CHEMBL612320)
Type ORGANISM
Organism Coxsackievirus B4

Publication

Highly potent and selective phosphatidylinositol 4-kinase IIIβ inhibitors as broad-spectrum anti-rhinoviral agents.
G Vishakantegowda A, Hwang D, Chakrasali P, Jung E, Lee JY, Shin JS, Jung YS.
RSC Med Chem (2024) 15 : 704 -719
PubMed 38389877 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.51 7.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5432195 1 7.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5432195 EC50 = 31.0 nM 7.51