Assay Detail
Binding
CHEMBL5380966
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rearranged during transfection kinase (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Proto-oncogene tyrosine-protein kinase receptor Ret (CHEMBL2041) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Fragment-to-Lead Medicinal Chemistry Publications in 2021.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.04 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388593 | — | — | 1 | 5.04 |
| CHEMBL5429146 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388593 | — | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL5429146 | — | IC50 | = | - | nM | - |