Assay Detail

CHEMBL5381309

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Binding

Inhibition of CBP (unknown origin)

ChEMBL ↗

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Target

CREB-binding protein (CHEMBL5747) ↗

Open DB target context

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CREB-binding protein (CHEMBL5747) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target CREB-binding protein

CHEMBL5747

Anchored from Assay target.

Protein identity CREB-binding protein

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

CREB-binding protein (CHEMBL5747) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Recent Advances on Small-Molecule Bromodomain-Containing Histone Acetyltransferase Inhibitors.

Liu M, Zhang K, Li Q, Pang H, Pan Z, Huang X, Wang L, Wu F, He G.
J Med Chem (2023) 66 : 1678 -1699
PubMed 36695774 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.49	6.49

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3752296	—	—	1	6.49

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3752296	—	IC50	=	323.0	nM	6.49