Assay Detail
Binding
CHEMBL5382182
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Binding affinity to CK2 (unknown origin)
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Strategies of Targeting CK2 in Drug Discovery: Challenges, Opportunities, and Emerging Prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.51 | 6.68 |
| Kd | 3 | 4.51 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150 | KAEMPFEROL | 1.0 | 1 | 6.68 |
| CHEMBL151 | LUTEOLIN | 2.0 | 1 | 6.62 |
| CHEMBL32749 | FERULATE | -1.0 | 1 | 6.39 |
| CHEMBL28 | APIGENIN | — | 1 | 6.36 |
| CHEMBL4224990 | — | — | 1 | 4.77 |
| CHEMBL5408174 | — | — | 1 | 4.24 |
| CHEMBL4117419 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150 | KAEMPFEROL | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL151 | LUTEOLIN | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL32749 | FERULATE | Ki | = | 410.0 | nM | 6.39 |
| CHEMBL28 | APIGENIN | Ki | = | 440.0 | nM | 6.36 |
| CHEMBL4224990 | — | Kd | = | 17000.0 | nM | 4.77 |
| CHEMBL5408174 | — | Kd | = | 58000.0 | nM | 4.24 |
| CHEMBL4117419 | — | Kd | = | 267000.0 | nM | - |