Assay Detail
Functional
CHEMBL5385076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse OX2R expressed in HEK293 cells by AP-TGFalpha reporter assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and Synthesis of Orexin 1 Receptor-Selective Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.75 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5203887 | — | — | 1 | 7.16 |
| CHEMBL5417451 | — | — | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5203887 | — | EC50 | = | 69.0 | nM | 7.16 |
| CHEMBL5417451 | — | EC50 | = | 457.0 | nM | 6.34 |