Assay Detail
Binding
CHEMBL5385387
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Inhibition of PKD1 (unknown origin) assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.14 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5405484 | — | — | 1 | 7.19 |
| CHEMBL4211840 | — | — | 1 | 7.18 |
| CHEMBL4209095 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5405484 | — | Ki | = | 64.0 | nM | 7.19 |
| CHEMBL4211840 | — | Ki | = | 66.0 | nM | 7.18 |
| CHEMBL4209095 | — | Ki | = | 89.0 | nM | 7.05 |