Assay Detail
Functional
CHEMBL5386549
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Antiproliferative activity against human U373 cells assessed as inhibition of cell growth measured after 72 hrs by CTG assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U373 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Natural quinazolinones: From a treasure house to promising anticancer leads.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL557488 | FUMITREMORGIN F | — | 1 | 4.05 |
| CHEMBL5436778 | — | — | 1 | - |
| CHEMBL5437139 | — | — | 1 | - |
| CHEMBL5417203 | — | — | 1 | - |
| CHEMBL5437191 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL557488 | FUMITREMORGIN F | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL5436778 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5437139 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5417203 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5437191 | — | IC50 | > | 100000.0 | nM | - |