Assay Detail
Binding
CHEMBL5386888
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Inhibition of TRPV1 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily V member 1 (CHEMBL4794) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Research progress and challenges of TRPV1 channel modulators as a prospective therapy for diabetic neuropathic pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.34 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL526 | PROPOFOL | 4.0 | 1 | 8.30 |
| CHEMBL294199 | CAPSAICIN | 4.0 | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL526 | PROPOFOL | IC50 | = | 5.05 | nM | 8.30 |
| CHEMBL294199 | CAPSAICIN | IC50 | = | 420.0 | nM | 6.38 |