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Assay Detail

CHEMBL5387097

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against asexual blood stage mefloquine-resistant Plasmodium falciparum Dd2 assessed as inhibition of parasitic growth
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Acyloxymethyl and alkoxycarbonyloxymethyl prodrugs of a fosmidomycin surrogate as antimalarial and antibacterial agents.
Courtens C, van Charante F, Quennesson T, Risseeuw M, Cos P, Caljon G, Coenye T, Van Calenbergh S.
Eur J Med Chem (2023) 245 : 114924 -114924
PubMed 36399924 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2164257 FOSMIDOMYCIN SODIUM 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2164257 FOSMIDOMYCIN SODIUM IC50 = 1100.0 nM 5.96