Assay Detail
Functional
CHEMBL5387518
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human beta-3 adrenoceptor expressed in CHO cells assessed as cAMP accumulation incubated for 10 mins by radioimmunoassay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Application and synthesis of thiazole ring in clinically approved drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.65 | 7.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2095212 | MIRABEGRON | 4.0 | 1 | 7.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2095212 | MIRABEGRON | EC50 | = | 22.4 | nM | 7.65 |