Assay Detail
Binding
CHEMBL5388049
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Binding affinity to ERR-gamma LBD (unknown origin) assessed as dissociation constant by ITC analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based discovery of pyrazolamides as novel ERRγ inverse agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.03 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5421673 | — | — | 1 | 5.19 |
| CHEMBL201013 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5421673 | — | Kd | = | 6500.0 | nM | 5.19 |
| CHEMBL201013 | — | Kd | = | 13600.0 | nM | 4.87 |