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Assay Detail

CHEMBL5389697

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 cells assessed as inhibition of viral replication
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Cell Type Vero E6
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

An ascidian Polycarpa aurata-derived pan-inhibitor against coronaviruses targeting M<sup>pro</sup>.
Zhang J, Zhao L, Bai Y, Li S, Zhang M, Wei B, Wang X, Xue Y, Li L, Ma G, Tang Y, Wang X.
Bioorg Med Chem Lett (2024) 103 : 129706 -129706
PubMed 38508325 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.39 5.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5403045 1 5.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5403045 EC50 = 4090.0 nM 5.39