Assay Detail
Binding
CHEMBL5389732
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human TRPM7 transfected in HEK293 cells assessed as inhibition of channel current by whole cell patch clamp analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily M member 7 (CHEMBL1250412) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Transient Receptor Potential Melastatin 7 (TRPM7) Ion Channel Inhibitors: Preliminary SAR and Conformational Studies of Xenicane Diterpenoids from the Hawaiian Soft Coral <i>Sarcothelia edmondsoni</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.57 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463843 | CANNABIGEROLIC ACID | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463843 | CANNABIGEROLIC ACID | IC50 | = | 2700.0 | nM | 5.57 |