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Assay Detail

CHEMBL5389751

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Rhizoctonia solani
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rhizoctonia solani
Confidence 1 — Organism
Curated By Autocuration

Target

Rhizoctonia solani (CHEMBL613272)
Type ORGANISM
Organism Rhizoctonia solani

Publication

Facile Synthesis and First Antifungal Exploration of Tetracyclic Meroterpenoids: (+)-Aureol, (-)-Pelorol, and Its Analogs.
Sun S, He X, Yang J, Wang X, Li S.
J Nat Prod (2024) 87 : 1092 -1102
PubMed 38557062 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 5 4.86 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL504264 AUREOL 1 5.16
CHEMBL487183 PELOROL 1 5.11
CHEMBL1736978 1 4.80
CHEMBL5424479 1 4.75
CHEMBL5406589 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL504264 AUREOL EC50 = 6900.0 nM 5.16
CHEMBL487183 PELOROL EC50 = 7700.0 nM 5.11
CHEMBL1736978 EC50 = 16000.0 nM 4.80
CHEMBL5424479 EC50 = 18000.0 nM 4.75
CHEMBL5406589 EC50 = 34000.0 nM 4.47