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Assay Detail

CHEMBL5390766

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human KB cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 1 — Organism
Curated By Autocuration

Target

KB (CHEMBL398)
Type CELL-LINE
Organism Homo sapiens

Publication

Cyclotheonellazoles D-I, Potent Elastase Inhibitory Thiazole-Containing Cyclic Peptides from <i>Theonella</i> sp. (2131).
Holland DC, Schroder WA, Calcott MJ, Kaemmerer E, Avery VM, Ekins MG, Carroll AR.
J Nat Prod (2023) 86 : 2216 -2227
PubMed 37609780 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.01 6.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5430373 1 6.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5430373 IC50 = 970.0 nM 6.01