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Assay Detail

CHEMBL5391412

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Functional
Cytotoxicity against human MCF7ADR cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI/ADR-RES
Confidence 1 — Organism
Curated By Autocuration

Target

NCI/ADR-RES (CHEMBL613829)
Type CELL-LINE
Organism Homo sapiens

Publication

The mechanisms of multidrug resistance of breast cancer and research progress on related reversal agents.
Yu S, Zheng J, Zhang Y, Meng D, Wang Y, Xu X, Liang N, Shabiti S, Zhang X, Wang Z, Yang Z, Mi P, Zheng X, Li W, Chen H.
Bioorg Med Chem (2023) 95 : 117486 -117486
PubMed 37847948 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL28 APIGENIN 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL28 APIGENIN IC50 = 200.0 nM 6.70