Assay Detail
Functional
CHEMBL5464239
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Hybrid reporter gene assay (RXRB) (These test systems rely on a chimera receptor containing only the ligand binding domain of the nuclear receptor in which is fused to the DNA binding domain from the yeast receptor Gal4. HEK293T cells)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe JP3000
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.85 | 8.85 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | These test systems rely on a chimera receptor containing only the ligand binding domain of the nuclear receptor in which is fused to the DNA binding domain from the yeast receptor Gal4. HEK293T cells |
| Target protein length | Target protein length | - | — | hinge region and LBD |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5404648 | — | — | 1 | 8.85 |
| CHEMBL5423123 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5404648 | — | EC50 | = | 1.4 | nM | 8.85 |
| CHEMBL5423123 | — | EC50 | > | 10000.0 | nM | - |