Assay Detail
Binding
CHEMBL5464244
Review assay metadata, readout intent, target linkage, and publication context from the same page.
SGK3 radioactive filter binding assay using 33P ATP (Dundee kinase screen)
2
Total Activities
2
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase Sgk3 (CHEMBL6186) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe SGK3-PROTAC1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.37 | 6.52 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 31461270 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795354 | — | — | 1 | 6.52 |
| CHEMBL5465169 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795354 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5465169 | — | IC50 | = | 600.0 | nM | 6.22 |