Assay Detail
Binding
CHEMBL5464362
Review assay metadata, readout intent, target linkage, and publication context from the same page.
% Activity remaining of SGK1 in the Dundee kinase panel at 1.0 µM
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase Sgk1 (CHEMBL2343) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe SGK3-PROTAC1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| % Activity remaining | 2 | - | - |
| IC50 | 2 | 6.26 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795354 | — | — | 2 | 6.66 |
| CHEMBL5465169 | — | — | 2 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795354 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL5465169 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4795354 | — | % Activity remaining | = | 34.49 | % | - |
| CHEMBL5465169 | — | % Activity remaining | = | 50.92 | % | - |