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Assay Detail

CHEMBL5464403

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Vasopressin V1A at 10.0 µM in the Eurofins-Panlabs selectivity screen
3
Total Activities
3
Compounds Tested
2
Activity Types
3
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vasopressin V1a receptor (CHEMBL1889)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Data for DCP probe BAY-9835
SGC Frankfurt
(2024)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.30 9.30
Inhibition 1 - -

Assay Parameters

Parameter Type Value Units Text
Assay publication Assay publication - https://www.eurofinsdiscovery.com/catalog/287530
Target protein length Target protein length - full length
Target protein type Target protein type - recombinant

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4594444 PECAVAPTAN 2.0 1 9.30
CHEMBL5465173 1 -
CHEMBL5575976 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4594444 PECAVAPTAN Ki = 0.5 nM 9.30
CHEMBL5465173 Ki > 10000.0 nM -
CHEMBL5575976 Inhibition = 7.0 % -