Assay Detail

CHEMBL5481198

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Binding

Selectivity interaction (Biochemical dose-responce assay (Carna Biosciences, Mobility shift assays)) EUB0001326b CDK4

ChEMBL ↗

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Target

CDK4/Cyclin D3 (CHEMBL3038472) ↗

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CDK4/Cyclin D3 (CHEMBL3038472) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target CDK4/Cyclin D3

CHEMBL3038472

Anchored from Assay target.

Protein identity CDK4/Cyclin D3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	7 — Homologous single protein target
Curated By	Autocuration

Target

CDK4/Cyclin D3 (CHEMBL3038472) ↗

Type	PROTEIN COMPLEX
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomic Library

EUbOPEN
(2024)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	9.59	9.59

Assay Parameters

Parameter	Type	Value	Units	Text
Protein family	Protein family	-	—	Protein kinase

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL189963	PALBOCICLIB	4.0	1	9.59

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL189963	PALBOCICLIB	Ki	=	0.26	nM	9.59