Assay Detail

CHEMBL5500469

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Functional

Cytotoxicity against human CAL-27 cells

ChEMBL ↗

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Target

CAL-27 (CHEMBL1075408) ↗

Open DB target context

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CAL-27 (CHEMBL1075408) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target CAL-27

CHEMBL1075408

Anchored from Assay target.

Protein identity CAL-27

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	CAL-27
Confidence	1 — Organism
Curated By	Autocuration

Target

CAL-27 (CHEMBL1075408) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities.

Zhang Z, Sun Y, Li Y, Song X, Wang R, Zhang D.
Eur J Med Chem (2024) 265 : 116081 -116081
PubMed 38181652 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.05	9.05

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5555337	—	—	1	9.05

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5555337	—	IC50	=	0.9	nM	9.05