Assay Detail
Functional
CHEMBL5500569
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.88 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL331627 | GLIOTOXIN | — | 1 | 7.10 |
| CHEMBL5555054 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL331627 | GLIOTOXIN | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL5555054 | — | IC50 | = | 220.0 | nM | 6.66 |