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Assay Detail

CHEMBL5501040

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NCI-H1703 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H1703
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H1703 (CHEMBL1075522)
Type CELL-LINE
Organism Homo sapiens

Publication

4-Hydroxy-2-pyridone derivatives with antitumor activity produced by mangrove endophytic fungus Talaromyces sp. CY-3.
Yang W, Zhang B, Tan Q, Chen Y, Chen T, Zou G, Sun B, Wang B, Yuan J, She Z.
Eur J Med Chem (2024) 269 : 116314 -116314
PubMed 38527379 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.18 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2179949 ILICICOLIN H 1 5.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2179949 ILICICOLIN H IC50 = 6650.0 nM 5.18