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Assay Detail

CHEMBL5501046

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse Lewis lung carcinoma cell line assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Lewis lung carcinoma
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

4-Hydroxy-2-pyridone derivatives with antitumor activity produced by mangrove endophytic fungus Talaromyces sp. CY-3.
Yang W, Zhang B, Tan Q, Chen Y, Chen T, Zou G, Sun B, Wang B, Yuan J, She Z.
Eur J Med Chem (2024) 269 : 116314 -116314
PubMed 38527379 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.24 5.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2179949 ILICICOLIN H 1 5.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2179949 ILICICOLIN H IC50 = 5780.0 nM 5.24