Assay Detail
Binding
CHEMBL5501340
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to His8-tagged human LC3B expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Microtubule-associated proteins 1A/1B light chain 3B (CHEMBL4879514) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting EGFR degradation by autophagosome degraders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.33 | 6.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL72365 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL72365 | — | Kd | = | 467.7 | nM | 6.33 |