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Assay Detail

CHEMBL5502120

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human U2OS cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter Aqueous One Solution Cell Proliferation Assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U2OS
Confidence 1 — Organism
Curated By Autocuration

Target

U2OS (CHEMBL615023)
Type CELL-LINE
Organism Homo sapiens

Publication

Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization.
Champiré A, Berabez R, Braka A, Cosson A, Corret J, Girardin C, Serrano A, Aci-Sèche S, Bonnet P, Josselin B, Brindeau P, Ruchaud S, Leguevel R, Chatterjee D, Mathea S, Knapp S, Brion R, Verrecchia F, Vallée B, Plé K, Bénédetti H, Routier S.
Eur J Med Chem (2024) 271 : 116391 -116391
PubMed 38669909 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.02 5.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5555717 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5555717 IC50 = 9500.0 nM 5.02