Assay Detail
Functional
CHEMBL5502638
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human LoVo cells harboring STAT3 over activation assessed as inhibition of cell growth measured after 24 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LoVo |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.26 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5558267 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5558267 | — | IC50 | = | 54.52 | nM | 7.26 |