Assay Detail
Binding
CHEMBL5503261
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild type BRAF (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase B-raf (CHEMBL5145) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.38 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5512465 | — | — | 1 | 7.70 |
| CHEMBL5518141 | — | — | 1 | 7.30 |
| CHEMBL5557132 | — | — | 1 | 7.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5512465 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5518141 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL5557132 | — | IC50 | = | 71.0 | nM | 7.15 |